The following assumes plenty boss+ armors and maybe a few older fusable epics, which result in, on the first few locations, knight 1 tanking about the first 4-5 screens and knight 2 finishing the run. Against the minions/mini bosses, you want to not be weak and being strong doesn't matter, while against the boss you want to non be weak and want to be 1 or 2 times strong. You encounter fewer minibosses than regular minions and their difference in damage is small, so if you can't be non-weak against all, focus on being non-weak to minions for the 1st knight. Also for the 1st knight, the more defensive the armor the better.
More to be added later.
|location||knight 1 good||knight 1 OK||knight 2 good||knight 2 OK||knight 3 good||knight 3 OK|
|Relic Ruins||anything without air||spirit, spirit/earth, spirit/water, spirit/fire|
|Thieves Cove||anything without fire||air, air/water, air/spirit, air/earth|
|Skeletons Tomb||water, spirit, water/spirit||earth, water/earth, spirit/earth||fire, fire/spirit, fire/air|
|Flaming Wildwood||anything without spirit||water/fire||water, fire, water/air, fire/air|
|Cold Rock Crags||anything without water or fire||anything without water||spirit, spirit/air, spirit/earth (maybe spirit/fire)||spirit/water|
|Faerie Forest||anything without earth or water||anything without earth||fire/spirit||fire, spirit, fire/air, spirit/air (maybe fire/water, spirit/water)|